Products for
In-Vitro Testing
After extensive research and development, we are pleased to introduce our novel DISCOVERY LANE products for in vitro testing, especially for screening drugs and mode of action studies of compounds/actives/molecules.
| Product Code | Product Name | Variations | Cell types/Tissues |
| CB-Epi-GM* | Epithelial Cells Growth Medium | SACF | Human Epidermal Keratinocytes, Oral epithelial cells |
| CB-Fib-GM | Fibroblast Growth Medium | FBS, XF, SACF | Dermal, Gingival, Placental |
| CB-DCM | Defined Cryopreservation Medium | SPACF | Sensitive primary cell and cell lines |
| CB-MSC-GM | Mesenchymal Stem Cell Growth Medium | With FBS, XF | Wharton jelly, Adipose, tooth pulp |
| CB-EC-GM | Endothelial cell growth medium | FBS, XF | Large and small vessel |
| CB-MC-GM | Melanocyte Growth Medium | FBS, XF | Melanocytes (All without Cholera toxin and PMA) |
| CB-EM-SKN | Explant Culture Medium for Skin | SACF, SF | Fresh Human Skin |
| CB-SCM-3D-MC | Spheroid Culture Medium for Mesenchymal cells | SACF | Mesenchymal cells/tumor cells |
| CB-TC-GM | Tumor Cell Growth Medium | SF | Breast and prostate cancer |
| CB-EM-PLAC | Explant Culture Medium for Placenta | SACF | Fresh human placenta |
| CB-DSC-GM | Dermal Stem Cell Growth Medium | XF | Dermal Stem cells |
| CB-Epi-3DAL** | 3D Epidermis Reconstruction Medium | SACF | Epidermal Keratinocytes |
| XF= Xeno-free; SPACF= Serum, Protein and Animal Component Free; SF= Serum-free; SACF= Serum and Animal Component Free; *Previous product code CB-TAK-GM; **Previous product code CB-TAK-3D | |||
| Products | Catalog Numbers | Variations |
|---|---|---|
| Explant Culture Medium for Skin | CB-EM-SKN CB-EM-SKN (SACF) | Serum-free; Serum & Animal Component Free |
| Fibroblast medium | CB-DF-GM | Xeno-free; Serum-free |
| Transiently Amplifying Keratinocyte medium | CB-TAK-GM | |
| Defined Cryo-preservation Medium | CB-DCM | Defined, Serum and Protein-free |
| Mesenchymal Stem Cell Growth Medium | CB-MSC-GM | Xeno-free |
| Melanocyte Growth Medium | CB-MC-GM | Xeno-free; Serum-free (both without Cholera toxin and PMA) |
| Endothelial Cell Growth Medium | CB-EC-GM | Xeno-free; Serum-free (For large vessel endothelial cells) |
| Spheroid Culture Medium for Mesenchymal cells | CB-SCM-3D-MC | |
| Explant Culture Medium for Placenta | CB-EM-PLAC | Serum-free |
| Epithelial Cell Growth Medium for Oral Keratinocytes | CB-Epi-GM-OK | |
| Cell Line Adaptation Kit | CB-CLAK | Only for service Purpose (Serum & Animal component Free) |
Advantages:
- An interference free-cell culture system: Culture media produced specially in our laboratory containing no unphysiological additives such as phenol-red, antibiotics, or inducers to enhance proliferation or to target/tune cultures to a particular progenitor.
- Components proved in the scientific literature: To achieve a natural growth environment, the cells are grown using a supplemental growth factor mix appropriate for the cell type that has been proved in the scientific literature (citations provided).
- Using appropriate cells: It is well known in the literature that same kinds of cells can be different functionally. For example, the gene profile of keratinocytes from oral tissue are different from epidermal keratinocytes (Reference 1) and cells derived from juvenile and adult donors (Reference 2) can differ.
- Pure cells: Beyond using selective growth factors for each cell type, our isolated cells are selected for purity using our proprietary combination of cell specific antigens for each cell type based on the literature (citations provided).
- Fully defined and animal component-free: Majority of products being used for in vitro testing are hormone and animal-component free and fully defined to avoid false positives
Note: There are several cell types for example fibroblasts, melanocytes, etc., that demand at least some small fraction of serum without which they cannot be initiated for cell growth. In this case, we grow the cells under Xeno-free conditions. We continue our efforts to be in line with the 3R motto motto: Reduce, Refine, Replace and develop new solutions for each cell type. Always we aim to develop the products for our clients projects in the most natural way, thereby mimicking all the mechanisms and physiological conditions as close as possible to the in vivo, but without the need of serum or unphysiological chemicals or inducers.
Areas:
- Dermatology
- Regenerative Biology
- Immunology
- Oncology
References:
1. PLoS One. 2014 Sep 8;9(9):e101480.
2. Int J Mol Med. 2016 Oct; 38(4): 1063–1074.
